American biologist who received the 2004 Nobel Prize in Chemistry for the discovery of ubiquitin-mediated protein degradation. He was a teacher at Yale College of Medicine’s section of biochemistry from 1954 to 1963. He received his B.S. in 1948, and his Ph.D. in biochemistry in 1952 through the College or university of Chicago. He offered in the Navy during Globe War II. He previously four children along with his wife Zelda Budenstein. He earned the Nobel Award four years before Martin Chalfie.